Alexander Mattison, Vikings, stepped in for the injured Dalvin Cook and racked up 171 total yards in a 30-17 win against Seattle.
Kareem Hunt, Browns, scored on a 29-yard run and finished with 155 yards, 81 rushing and 74 receiving, in a 26-6 victory against Chicago. Derrick Henry, the reigning AP NFL Offensive Player of the Year ran for 113 yards, topping the 100-yard mark for a sixth straight division game. Derek Carr, Raiders, completed 26 of 43 pass attempts for 386 yards and two touchdowns in a 31-28 overtime victory against Miami. Kirk Cousins, Vikings, went 30 for 38 for 323 yards in his third consecutive turnover-free game, throwing for three first-half TDs in a 30-17 win against Seattle. Josh Allen, Bills, finished 32 of 43 for 358 yards and four touchdowns, while also surpassing the 100-touchdown plateau (including TDs rushing and one receiving) in his 47th start. Kyler Murray, Cardinals, completed 28 of 34 passes for 316 yards and ran for a score in a 31-19 victory at Jacksonville.
